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Facial


Rejuran Healer is an injectable polynucleotide treatment used in aesthetic medicine to improve skin quality. It is commonly used for concerns such as fine lines, uneven texture and reduced elasticity.
Before-and-after results can vary depending on your skin condition, treatment area, number of sessions and individual response. This guide explains what Rejuran is, what changes you may notice, how long results can take and what to expect from the treatment process.

Rejuran Healer is an injectable skin treatment made with purified polynucleotides (PN) derived from salmonid DNA. It is used to support skin rejuvenation and may help improve concerns such as skin texture, hydration, elasticity and fine lines.
Polynucleotides are thought to support processes involved in skin hydration, tissue remodelling and collagen production.
Rather than adding significant facial volume like a traditional dermal filler, Rejuran is generally used to improve the overall quality and appearance of the skin. Results can vary, and the exact formulation depends on the Rejuran product used.
Research suggests that polynucleotide treatments may help improve:
However, the exact mechanism and degree of improvement are still being studied, and more high-quality research is needed.
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Before-and-after photos can help illustrate possible changes in skin texture, fine lines or overall appearance after Rejuran treatment.
However, they should not be treated as a guarantee of what your own results will look like.
Lighting, camera angle, facial expression, makeup, skincare and the timing of the photo can all affect how results appear.
When viewing before-and-after photos, look for images taken under similar lighting and positioning and consider them alongside information about the treatment timeline and number of sessions.
A 2025 systematic review of nine studies involving 219 patients found promising results for wrinkles, skin texture and elasticity, with generally mild and temporary side effects. However, the studies were mostly of low to moderate quality, so larger and better-designed research is still needed.
Rejuran is administered through multiple small injections into selected areas of the skin by a qualified medical practitioner.
A topical numbing cream may be applied beforehand to reduce discomfort. The exact injection technique, amount used and treatment areas depend on the product and your individual treatment plan.

Before treatment, your practitioner will assess your skin concerns, medical history and treatment goals.
This is also an opportunity to discuss what Rejuran may realistically help with, how many treatments may be considered and whether another treatment might be more appropriate for your concerns.
After cleansing and preparing the skin, small amounts of the product are injected into selected areas.
Because Rejuran is delivered by injection, it should be described as a minimally invasive injectable treatment, rather than a non-invasive treatment.
Some discomfort may occur during the injections, although numbing cream is commonly used beforehand.
Temporary effects such as redness, swelling, tenderness, bruising or small raised bumps at the injection sites can occur.
These effects are generally temporary, although recovery varies between individuals.
Follow the aftercare instructions given by your treating practitioner and contact the clinic if symptoms are severe, worsening or do not improve as expected.
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Polynucleotide treatments have been explored for skin remodelling and acne-scar concerns, but research specifically supporting their use for acne scars remains limited.
Acne scars also vary in type and depth. Treatments such as lasers, microneedling, subcision or other medical procedures may be more appropriate for some scars.
A professional assessment can help determine which treatment is more suitable.
Key Takeaways
While Rejuran is an injectable treatment aimed at improving skin quality, facials offer a non-invasive way to complement your regular skincare routine and support hydration, smoother-looking texture and a refreshed complexion.
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