Facial

Rejuran Healer Before and After: What You Need To Know

blog-main-img
woman touching her face

Rejuran Healer is an injectable polynucleotide treatment used in aesthetic medicine to improve skin quality. It is commonly used for concerns such as fine lines, uneven texture and reduced elasticity.

Before-and-after results can vary depending on your skin condition, treatment area, number of sessions and individual response. This guide explains what Rejuran is, what changes you may notice, how long results can take and what to expect from the treatment process.

What Is Rejuran Healer and What Is It Made Of?

medical syringe on a white surface.

Rejuran Healer is an injectable skin treatment made with purified polynucleotides (PN) derived from salmonid DNA. It is used to support skin rejuvenation and may help improve concerns such as skin texture, hydration, elasticity and fine lines.

How Does Rejuran Healer Work?

Polynucleotides are thought to support processes involved in skin hydration, tissue remodelling and collagen production.

Rather than adding significant facial volume like a traditional dermal filler, Rejuran is generally used to improve the overall quality and appearance of the skin. Results can vary, and the exact formulation depends on the Rejuran product used.

Research suggests that polynucleotide treatments may help improve:

  • Fine lines and wrinkles
  • Skin texture
  • Skin elasticity
  • Hydration
  • Overall skin appearance

However, the exact mechanism and degree of improvement are still being studied, and more high-quality research is needed.

What Can Rejuran Before-and-After Photos Show?

woman touching her smooth, glowing skin.

Before-and-after photos can help illustrate possible changes in skin texture, fine lines or overall appearance after Rejuran treatment.

However, they should not be treated as a guarantee of what your own results will look like.

Lighting, camera angle, facial expression, makeup, skincare and the timing of the photo can all affect how results appear.

When viewing before-and-after photos, look for images taken under similar lighting and positioning and consider them alongside information about the treatment timeline and number of sessions.

What Does Research Say About Rejuran?

A 2025 systematic review of nine studies involving 219 patients found promising results for wrinkles, skin texture and elasticity, with generally mild and temporary side effects. However, the studies were mostly of low to moderate quality, so larger and better-designed research is still needed.

What Research Has Studied What It Suggests Important Limitation
Fine lines and wrinkles Some studies have reported improvements after polynucleotide treatment. Results vary, and the available studies are still limited.
Skin texture Improvements in texture and overall skin quality have been reported. Study methods and treatment protocols differ.
Skin elasticity Some research has found improvements in skin elasticity. More high-quality comparative studies are needed.
Hydration Polynucleotide treatments may help support skin hydration. The degree of improvement varies between individuals.
Safety Published studies generally report mostly temporary injection-site effects. Long-term and large-scale evidence is still limited.

Rejuran Healer Treatment Process

Rejuran is administered through multiple small injections into selected areas of the skin by a qualified medical practitioner.

A topical numbing cream may be applied beforehand to reduce discomfort. The exact injection technique, amount used and treatment areas depend on the product and your individual treatment plan.

close-up of redness on woman's face

1. Consultation and Assessment

Before treatment, your practitioner will assess your skin concerns, medical history and treatment goals.

This is also an opportunity to discuss what Rejuran may realistically help with, how many treatments may be considered and whether another treatment might be more appropriate for your concerns.

2. Treatment

After cleansing and preparing the skin, small amounts of the product are injected into selected areas.

Because Rejuran is delivered by injection, it should be described as a minimally invasive injectable treatment, rather than a non-invasive treatment.

Some discomfort may occur during the injections, although numbing cream is commonly used beforehand.

3. After Treatment 

Temporary effects such as redness, swelling, tenderness, bruising or small raised bumps at the injection sites can occur.

These effects are generally temporary, although recovery varies between individuals.

Follow the aftercare instructions given by your treating practitioner and contact the clinic if symptoms are severe, worsening or do not improve as expected.

Timeline What You May Notice
Immediately after treatment Temporary redness, swelling, tenderness or small injection bumps may occur.
Following days Injection-site effects generally begin to settle, although recovery varies between individuals.
Following weeks Changes in skin texture, fine lines or overall appearance may gradually become noticeable.
Over multiple sessions Some people may notice further improvement depending on their treatment plan, skin concerns and individual response.

Is Rejuran Suitable for Acne Scars?

doctor consulting with a female patient.

Polynucleotide treatments have been explored for skin remodelling and acne-scar concerns, but research specifically supporting their use for acne scars remains limited.

Acne scars also vary in type and depth. Treatments such as lasers, microneedling, subcision or other medical procedures may be more appropriate for some scars.

A professional assessment can help determine which treatment is more suitable.

Key Takeaways

  • Rejuran is a minimally invasive injectable treatment containing purified polynucleotides.
  • It is mainly used to improve skin quality rather than significantly change facial volume or structure.
  • Research has reported possible improvements in wrinkles, texture, elasticity and hydration.
  • Results vary and generally develop gradually rather than immediately.
  • Temporary redness, swelling, tenderness or small injection bumps may occur after treatment.
  • Before-and-after photos can illustrate possible changes but should not be treated as guaranteed results.
  • Current research is promising, but larger and higher-quality studies are still needed.

While Rejuran is an injectable treatment aimed at improving skin quality, facials offer a non-invasive way to complement your regular skincare routine and support hydration, smoother-looking texture and a refreshed complexion.

Kosme Aesthetics Facial Promo

Your skin deserves a little extra care. Add a facial to your skincare routine and enjoy our exclusive $50 facial trial!

Frequently Asked Questions

How long does it take for Rejuran to work?

How many sessions of Rejuran Healer are needed?

Is Rejuran healer worth it?

Is Rejuran a Dermal Filler?

What Are the Side Effects of Rejuran?

Our Big Promise and 3 No's

No Packages.

No Hidden Fees.

No Hard-selling.

Book Now

Our Big Promise and 3 No's

No Packages.

No Hidden Fees.

No Hard-selling.

Book Now